atural progesterone cream is a natural hormonal product.
The hormone progesterone has countless functions in the body: regulating periods and pregnancy in women, sperm production in men, building bones, regulating blood sugar and body fat stores, developing intelligence, brain activity, sleep regulation, immune function, kidney function and many more.
Natural progesterone therapy has been practiced for over 50 years in the treatment of a wide variety of symptoms and diseases that are hormonally related. During this time no adverse side effects have been reported.*
Recommendations on how to use Natural Progesterone Cream:
To use apply 1/4 teaspoon (pea-sized amount) externally by rubbing cream onto unbroken skin (it is a good idea to vary the area to improve absorption and use thin skin e.g. inside of wrist, over collarbone) or apply vaginally (believed to improve absorption). Do this morning and night.
Menstruating women with regular cycles (otherwise follow calendar month as below):
- Stop using the cream when your period begins and re-start when it has stopped.
- If you have any new mid-cycle bleeding consult your GP.
Post-menopausal (periods absent), post hysterectomy or while pregnant/ breast-feeding:
- Count the first day of the calendar month as Day 1. Apply cream as directed above but stop on Day 27 and resume the following month on Day 1.
- If you have any new bleeding over 12 months after periods have stopped, consult your GP.
- Apply 1/4 teaspoon of the cream onto unbroken skin once daily. Stop on Day 27 of the calendar month and resume on the 1st of the following month.
* Many people are confused between natural progesterone and the synthetic progestins, medications which are also commonly called Progesterone. They have many side effects and are not the same as natural progesterone cream.
- Dr John Lee & Virginia Hopkins (2005). What Your Doctor May Not Tell You About Menopause.
- Dr John Lee, David Zava, Virginia Hopkins (2005). What Your Doctor May Not Tell You About Breast Cancer: How Hormone Balance Can Save Your Life.
- Dr John Lee & Virginia Hopkins (2006). Dr John Lee’s Hormone Balance Made Simple: The Essential How-to Guide to Symptoms, Dosage, Timing and More.
- Dr John Lee (2003). Hormone Balance for Men. Available to download here
You can listen to one of his lectures on progesterone for free here
Published information on Natural Progesterone cream:
- Chang, K.J. et al (1995). Influences of percutaneous administration of estradiol and progesterone on human breast epithelial cell cycle in vivo. Fertil Steril. 63, 785-791
- Cowan, L. et al (1985). Breast Cancer incidence in women with Progesterone deficiency. Am. J. Epidemiol. 114 (2), 209-217
- Fitzpatrick, L. et al (2000). Comparison of regimens containing oral micronized progesterone or medroxyprogesterone acetate on quality of life in postmenopausal women: A cross-sectional survey. Journal of Women’s Health Gender-based Medicine. 9 (4), 381-7 (“The side effects of the synthetics include bloating, nausea and depression were eliminated by using natural progesterone. In fact unexpected improvement in the feeling of well-being was observed when natural progesterone was used“)
- Formby, B. and Wiley, T.S. (1998). Progesterone inhibits growth and induces apoptosis in breast cancer cells: inversive effects on Bcl-2 and p53. Ann Clin Lab Sci. 28, 360-69
- Hermsmeyer, R.K. et al (2004). Prevention of coronary hyper-reactivity in pre-arthrogenic menopausal rhesus monkeys by transdermal progesterone. Arterioscler Thromb Vasc Biol. 24, 955-61
- Lee, J. R. (1990). Osteoporosis Reversal. The Role of Progesterone. Int Clin Nutr Rev. 10 (3), 384-91
- Lee, J. R. (1995). Natural Progesterone: The Multiple Roles of a Remarkable Hormone. BLL Publishing: California
- Lee, W.S. et al (1997). Progesterone inhibits arterial smooth muscle proliferation. Nat Med. 3, 1005-8
- Leonetti, H.B. et al (1999). Transdermal Progesterone cream for vasomotor symptoms and postmenopausal bone loss. Obstet Gynecol 94 (2), 225-8
- Murray, J. Natural Progesterone: What Role in Women’s Healthcare?. Available from: http://womeninbalance.org/choices-in-therapy/hormone-treatment-options/ (respected US Doctor M.D. and former head of the American Academy of Family Physicians argues there have been no studies to date of any harm to women from Natural Progesterone)
- The writing group for the PEPI Trial (1995). Effects of Estrogen/ Progestin regimens on heart disease risk factors in postmenopausal women. The PostmenopausalEstogen/ Progestin Interventions PEPI trial. JAMA. 273 (3), 199-208 Trials show Natural Progesterone more effective than synthetic
- Ryan, N. and Rosner, A. (2001). Quality of life and costs associated with micronized progesterone and medroxyprogesterone acetate in hormone replacement therapy for nonhysterectomized, postmenopausal women. Clin Ther. 23, 1099-1115
- Rylance, P.B. et al (1985). Natural Progesterone ad anti-hypertensive action. Br Med J (Clin Res Ed). 290 (6461), 13-14
- Schumacher, M. et al (2004). Local synthesis and dual actions of progesteone in the nervous system: Neuroprotection and myelination. Growth Horm IGF Res. 14, S18-33
- Stephenson, K. et al (2004). Progesterone does not increase thrombotic and inflammatory factors in postmenopausal women. Blood. 104 (16).
- Wright, J.V. & Morgenthaler, J. (1997). Natural Progesterone. Smart Publications: California